| NCT06538974 | Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and / or Deficiencies in Adult Population | Wandercraft | | - Age ≥ 18 yrs
- Level C1-S5
AIS - All
| Recruiting | 100 | NA | Rehabilitation | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Adverse Events (AEs)
- Functional Independence Measure (FIM)
- Neurogenic Bowel Dysfunction Score (NBD or NBDS)
- System Usability Scale (SUS)
- Timed Up and Go Test (TUG)
| 2 years | 16 February 2023 | 06 August 2024 | 1 | |
| NCT06690372 | Improving Heart Health in Individuals With SCI Using Home-Based Virtual Gaming | Drexel University | | - Age ≥ 18 yrs
- Level C1-S5
AIS A, B, C, D- All
- be wheelchair users (at least 75% of community mobility)
| Recruiting soon | 16 | NA | Rehabilitation | General health | - Blood Pressure and Heart Rate Regulation
- Brief Pain Inventory (BPI)
- Exercise Self-Efficacy Scale (ESES)
- Feasibility
- Pain Numeric Rating Scale (NRS)
- Patient Health Questionnaire-9 (PHQ-9)
| 16 weeks | 01 December 2025 | 15 November 2024 | 1 | |
| NCT06698224 | Paired Spinal Cord and Peripheral Nerve Stimulation to Recover Hand Function in SCI | Kessler Foundation | | - Age ≥ 18 yrs
- Level C1-T1
AIS - ≥ 6 months
- NOT have metal implant in the head
- NOT have a cardiac pacemaker
- NOT have an implanted brain stimulator
- NOT have an implanted pump (e.g., baclofen pump or pain pump)
| Recruiting soon | 14 | NA | Rehabilitation | Arm/hand function | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Capabilities of Upper Extremity Instrument (CUE- Q and CUE-T)
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Motor Evoked Potentials (MEPs)
- Pain Numeric Rating Scale (NRS)
- Surface Electromyography (sEMG)
| 4 weeks | 02 January 2025 | 20 November 2024 | 1 | |
| NCT06514950 | Yoga Breath Training to Improve Cardiorespiratory Synchrony in Spinal Cord Injury | Spaulding Rehabilitation Hospital | | - Age 18 - 60 yrs
- Level C1-S5
AIS A, B, C- All
- be a wheelchair user
- NOT suffer from any other pulmonary, coronary artery, or neurological disease
- NOT currently be using tobacco or cardioactive medications (unless used to support blood pressure)
| Recruiting | 20 | NA | Psychosocial/other | General health | - Blood Pressure and Heart Rate Regulation
| 6 weeks | 01 August 2024 | 23 July 2024 | 1 | |
| NCT06272279 | Neuromodulation With Spinal Stimulation Methods | University of Manitoba | | - Age 18 - 65 yrs
- Level C4-L4
AIS - All
- NOT have a history of seizures
- NOT have metal implants including electronic medical devices
| Recruiting | 24 | NA | Technology | General health | - Blood Pressure and Heart Rate Regulation
- H reflex
- Motor Evoked Potentials (MEPs)
| 15 minutes | 01 March 2024 | 22 February 2024 | 1 | |
| NCT06247904 | NIBS Therapy in Subacute Spinal Cord Injury | Albert Einstein Healthcare Network | | - Age 18 - 80 yrs
- Level C4-C6
AIS A, B, C- All
- NOT have trauma-related brain injury
- NO history of seizures or seizure risk
| By invitation | 20 | NA | Technology | General health | - Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Feasibility
- Motor Evoked Potentials (MEPs)
| 2 years | 09 April 2025 | 08 February 2024 | 1 | |
