| NCT03780829 | AIH for Spinal Cord Repair | VA Office of Research and Development | | - Age 18 - 80 yrs
- Level C1-C8
AIS A, B, C, D- 1 years - 99 years
- have impaired sensation and strength in the hands, but able to grasp small objects with one hand and able to grasp between the index finger and thumb
- be right handed
- NOT have a pacemaker
| Recruiting | 90 | EARLY_PHASE1 | Drug | Arm/hand function | | | 25 February 2020 | 19 December 2018 | 1 | |
| NCT03774043 | Timing and Dosage of Acute Intermittent Hypoxia in Persons With SCI | Shirley Ryan AbilityLab | | - Age 18 - 70 yrs
- Level C3-T1
AIS C, D- 6 months - 70 years
- NOT have an anti-spasticity drug injection within 3 months of treatment
| | 24 | PHASE1, PHASE2 | Drug | Arm/hand function | | | 01 May 2016 | 12 December 2018 | 1 | |
| NCT03762655 | Study of Probable Benefit of the Neuro-Spinal Scaffold™ in Subjects With Complete Thoracic AIS A Spinal Cord Injury as Compared to Standard of Care | InVivo Therapeutics | | - Age 16 - 70 yrs
- Level T2-T12
AIS A- ≤ 7 days
- have a non-penetrating SCI (contusion or crush type of SCI).
| Ended | 20 | NA | Surgery | General health | | | 21 May 2019 | 04 December 2018 | 18 | |
| NCT03721861 | Use of Neural Functional Electrical Stimulation for the Recovery of Grasping Movements for Patient With Quadriplegia. | Clinique Beau Soleil | | - Age 18 - 65 yrs
- Level C1-C7
AIS A, B- 6 months - 65 years
- be scheduled to undergo clinically-indicated rehabilitative upper extremity surgery.
- have no change in muscle strength testing in the past 6 months.
- have no or almost no muscle function below the elbow.
- have a body weight below 220 lbs (<100kg).
- NOT be wearing a pacemaker
| Ended | 9 | NA | Technology | Arm/hand function | | | 09 February 2016 | 26 October 2018 | 1 | |
| NCT03714997 | High Intensity Exercise in Incomplete SCI | Indiana University | | - Age 18 - 75 yrs
- Level C1-T10
AIS C, D- 1 years - 75 years
- be able to tolerate 10 minutes of standing without blood pressure problems.
- have a body weight lower than 400 lbs (= 181 kg).
- NOT be dependent on a ventilator
- NOT be undergoing concurrent physical therapy
| Ended | 53 | NA | Rehabilitation | Standing/walking/mobility | | | 01 July 2019 | 22 October 2018 | 1 | |
| NCT03702842 | Stimulation to Enhance Walking Post-SCI | University of Florida | | - Age 18 - 65 yrs
- Level C1-T12
AIS C, D- 1 years - 65 years
- be capable of walking at least 10 feet (= 3 meters) with gait devices or help.
- NOT have pain, spasticity, skin lesions or contractures that limit walking
- NOT have implanted hardware below 8th thoracic vertebrae
| Ended | 8 | NA | Technology | Standing/walking/mobility | | | 01 April 2019 | 11 October 2018 | 1 | |