All trials - page: 25

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NCTID
Brief title
Sponsor
Design
Criteria
Status
Target enrollment
Study phase & design
Primary intervention type
Primary potential benefit
Outcome measure
Follow up
Start date
First posted
Location
NCT07024407A Study of Andecaliximab in People With Spinal Cord Injury at Risk for Bone Growth Outside of the Normal Skeleton.Ashibio Inc
  • Age 18 - 89 yrs
  • Level C1-S5
  • AIS
  • ≥ 10 days
Recruiting10PHASE1, PHASE2DrugGeneral health
  • Adverse Events (AEs)
13 weeks14 May 202517 June 20251
NCT06828653Comparing Digitally and Traditionally Made Ankle Foot OrthosesHolland Bloorview Kids Rehabilitation Hospital
  • Age ≥ 8 yrs
  • Level C1-S5
  • AIS
  • All
  • Require the use of an AFO to improve physical functioning
  • Be able to ambulate independently
  • Meet requirements for AFO funding by the Assistive Device Program in Ontario, Canada
Recruiting50NATechnologyStanding/walking/mobility
  • 10 Meter Walking Test (10 MWT)
  • Goal Attainment Scaling (GAS) score
  • Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST)
  • Timed Up and Go Test (TUG)
14 weeks05 September 202514 February 20252
NCT06873776Arm and Leg Cycling for Accelerated SCI RecoveryShirley Ryan AbilityLab
  • Age 18 - 75 yrs
  • Level C1-T11
  • AIS C, D
  • ≥ 1 years
  • Be able to ambulate independently for at least 10 meters
  • Ambulate with maximum walking speed of less than 0.8 meters/second
  • Have bilateral arm strength to independently arm cycle 15 minutes
By invitation40NARehabilitationStanding/walking/mobility
  • 10 Meter Walking Test (10 MWT)
  • 6-Minute Walk Test (6MWT)
  • Ashworth and Modified Ashworth Scale (MAS)
  • Berg Balance Scale (BBS)
  • Motor Evoked Potentials (MEPs)
  • Sensory evoked potentials (including mixed and dermatomal, mSSEPs, dSSEPs, contact heat/laser evoked potentials- CHEPS/LEPs)
  • Surface Electromyography (sEMG)
  • Walking Index for Spinal Cord Injury (WISCI) and WISCI II
6 months01 December 202513 March 20251
NCT06922890First-in-Human Clinical Trial of STUP-001, an In Vivo Direct Cell Conversion Gene Therapy for AIS-A/B Chronic Spinal Cord InjuryYonsei University
  • Age 19 - 60 yrs
  • Level C1-S5
  • AIS A, B
  • ≥ 6 months
  • Be able to undergo general anesthesia
  • Be able to provide evidence of non-fertile status, if female
  • NOT have significant contraindications for elective surgery
  • NOT have a history of malignancy within the previous 5 years
Recruiting9PHASE1, PHASE2DrugGeneral health
  • Adverse Events (AEs)
7 months30 July 202511 April 20252
NCT06978205Effect of Urethral Balloon Dilatation on Urinary Retention After Spinal Cord InjuryQilu Hospital of Shandong University
  • Age 18 - 80 yrs
  • Level C1-S5
  • AIS
  • All
  • Have urinary retention with post-void residual volume more than 300ml
  • Have urodynamic evidence of maximal urethral pressure >50cmH2O
  • NOT use an indwelling urinary catherter for bladder management
  • NOT have a urinary tract infection
Recruiting74NATechnologyBladder health/function
  • Hospital Anxiety and Depression Scale (HADS)
  • Neurogenic Bladder Symptom Score
  • Qualiveen
3 weeks28 April 202518 May 20251
NCT07019207Virtual Reality Dual Task Training in SCI: Effects on Cognition and Cortical ActivationIstinye University
  • Age 18 - 60 yrs
  • Level T1-S5
  • AIS
  • ≥ 3 months
  • Have active shoulder flexion and abduction of at least 90 degrees
  • Be able to sit in a chair for at least 30 minutes
  • NOT have musculoskeletal pain >5 out of 10 on the Visual Analog Scale
  • NOT have a history of significant head trauma
Recruiting soon45NARehabilitationGeneral health
  • Canadian Occupational Performance Measure
  • Fugl-Meyer Assessment (FMA)
  • Hand-Held Myometery / Dynamometry
  • Modified Functional Reach Test (mFRT)
6 weeks16 June 202513 June 20252