| NCT07105878 | Epidural Electrical Stimulation in Spinal Cord Injury | Second Affiliated Hospital, School of Medicine, Zhejiang University | | - Age 18 - 60 yrs
- Level T1-T10
AIS B, C, D- 4 months - 18 months
- NOT have implanted cardiac pacemakers, cardioverters, or defibrillators
| Recruiting | 10 | NA | Technology | General health | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Ashworth and Modified Ashworth Scale (MAS)
- Functional Independence Measure (FIM)
- Motor Evoked Potentials (MEPs)
- Penn Spasm Frequency Scale (PSFS)
- Sensory evoked potentials (including mixed and dermatomal, mSSEPs, dSSEPs, contact heat/laser evoked potentials- CHEPS/LEPs)
- Short Form 36 (SF-36)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 6 months | 01 March 2025 | 06 August 2025 | 1 | |
| NCT07222046 | Spinal Neurorehabilitation for Veterans With SCI | VA Office of Research and Development | | - Age ≥ 18 yrs
- Level C1-S5
AIS - ≥ 12 months
- NOT have epilepsy, intracranial metal, implanted electro-sensitive devices, or other contraindications to the use of external magnetic or electrical stimulation
| Recruiting soon | 40 | NA | Technology | General health | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Electromyography
- Magnetic Resonance Imaging (MRI) - conventional/anatomical and quantitative
- Sensory evoked potentials (including mixed and dermatomal, mSSEPs, dSSEPs, contact heat/laser evoked potentials- CHEPS/LEPs)
| 5 years | 23 January 2026 | 29 October 2025 | 1 | |
| NCT07210879 | Early Predictors for Neurological Outcome After Traumatic Spinal Cord Injury | BG Unfallklinik Murnau | | - Age ≥ 18 yrs
- Level C1-S5
AIS - ≤ 2 years
| Active | 800 | | | General health | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
| 1.5 years | 20 July 2022 | 07 October 2025 | 1 | |
| NCT07101042 | Cold vs. Paraspinal Stimulation for Erectile and Urinary Function in SCI Patients | Cairo University | | - Age 25 - 55 yrs
- Level T1-L5
AIS - ≥ 6 months
- NOT have implanted electrical devices (e.g., pacemakers)
| Recruiting soon | 30 | NA | Technology | Sexual health | | 4 weeks | 01 September 2025 | 03 August 2025 | 0 | |
| NCT07042815 | Long-term Follow-up for Epidural Stimulation in SCI | Kessler Foundation | | - Age ≥ 18 yrs
- Level C1-S5
AIS - All
- have received a neurostimulator and electrode array as part of a previous study
| By invitation | 91 | NA | Technology | Standing/walking/mobility | - Blood Pressure and Heart Rate Regulation
- Bowel and bladder control
- Magnetic Resonance Imaging (MRI) - conventional/anatomical and quantitative
| 1 year | 13 January 2025 | 29 June 2025 | 1 | |
| NCT06989905 | MEP Up-conditioning to Target Corticospinal Plasticity | Medical University of South Carolina | | - Age ≥ 18 yrs
- Level C1-C6
AIS - ≥ 6 months
- NOT have metal implants in the cranium
- NOT have implanted biomedical device in or above the chest (e.g., a cardiac pacemaker, cochlear implant)
| Recruiting | 11 | EARLY_PHASE1 | Technology | Mechanism of action | - Capabilities of Upper Extremity Instrument (CUE- Q and CUE-T)
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Motor Evoked Potentials (MEPs)
- Spinal Cord Independence Measure (SCIM)
| 3 months | 27 May 2025 | 25 May 2025 | 1 | |
