Epidural Electrical Stimulation in Spinal Cord Injury (T11-L3)

Technology
Standing/walking/mobility
Online since 20 January 2026, updated today

About this trial

This trial is enrolling 10 participants with spinal cord injury to test the effect of epidural spinal stimulation (eSS) combined with standard rehabilitation therapy on motor and sensory function. eSS is an invasive technique that uses implanted electrodes placed next to the spinal cord to deliver electrical stimulation aimed at modifying spinal cord function. If included, participants will undergo surgical implantation of an eSS device and receive individualized stimulation programming. Final testing of motor and sensory function will be performed 6 months after device implantation.

Included participants

Gender
All
Age
16 - 65 years
Injury level
T11 - L3
  • Severity (AIS)?
  • AIS-B
    AIS-C
    AIS-D
    Time since injury
    2 months - 2 years
    Healthy volunteers
    No
    T11-L3
    Additionally, participants must
    NOT have implanted cardiac pacemakers, cardioverters, or defibrillators

    What’s involved

    Type

    Technology

    Details

    - Participants will undergo surgical implantation of an epidural spinal stimulation (eSS) device, receive individualized stimulation programming, and participate in structured rehabilitation therapy. - eSS is an invasive technique that uses an implanted electrode placed next to the spinal cord to deliver electrical stimulation aimed at modifying spinal cord function. - Final testing of motor and sensory function will be performed 6 months after device implantation.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    Arm/hand function

    General health

    Mental health and psychosocial factors

    Pain

    Sensory function

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Jul 2025
    • Organisation
    • Second Affiliated Hospital, School of Medicine, Zhejiang University
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Jul 2025
    • Organisation
    • Second Affiliated Hospital, School of Medicine, Zhejiang University

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more